Negative Studies of Depression Meds Remain Unpublished – Health Blog – WSJ

Industry-sponsored studies of antidepressants that come up with positive results are more likely to be published than those that come up with negative results, says a paper in this week’s New England Journal of Medicine.

The authors looked at 74 antidepressant studies that had been filed with the FDA, and found that those deemed positive by the agency went unpublished only 3% of the time, while those deemed negative by the agency went unpublished 67% of the time. When unfavorable studies were published, it was in a way that conflicted with the FDA’s opinion of the study, according to the article.